1. In Alzheimer’s disease, cerebral plaques consist of:
a) ATTR protein
b) Aβ2M protein
c) Prion protein
d) Aβ protein
2. Amyloid enhancing factor (AEF) plays a significant role in:
a) Primary amyloid
b) Secondary amyloid
c) Senile cerebral amyloid
d) Haemodialysis-associated amyloid
3. Non-fibrillar amyloid components include all except:
a) Amyloid P component
b) Apolipoprotein E
c) Protein X
d) Cystatin
4. Grave’s disease is a type of:
a) Type I reaction
b) Type II reaction
c) Type III reaction
d) Type IV reaction
5. Which of the following is heredo-familial form of amyloidosis?
a) Polyneuropathic amyloidosis
b) Cardiac amyloidosis
c) Cerebral amyloidosis
d) Endocrine amyloidosis
6. CD4 T cell count in crisis phase of HIV according to revised HIV/AIDS classification is:
a) < 100/ microlitre
b) < 200/ microlitre
c) < 250/ microlitre
d) < 500/ microlitre
7. Test useful for detection of HIV during window period:
a) ELISA
b) Western blot
c) CD4+ cell count
d) p24 antigen capture assay
8. Haematoxylin body represents:
a) Cytosolic components
b) RNA
c) Nuclear chromatin material
d) Cell membrane components
9. For counting of CD4 + T cells in AIDS, the following technique is often employed:
a) In situ hybridisation
b) Polymerase chain reaction
c) Flow cytometry
d) Electron microscopy
10. For karyotyping, the dividing cells are arrested by addition of colchicine in the following mitotic phase:
a) Prophase
b) Metaphase
c) Anaphase
d) Telophase