1. Transplantation antigens are located on portion of:
a) Chromosome 1
b) Chromosome 6
c) Chromosome 9
d) Chromosome 22
2. Class I HLA antigens are located on:
a) All nucleated cells of the body
b) B and T lymphocytes
c) Macrophages
d) Complement system
3. HIV contaminated waste products can be decontaminated by the following agents except:
a) Sodium hypochlorite
b) Formaldehyde
c) Methanol
d) Glutaraldehyde
4. CD4 bearing subpopulation of macrophages are attacked by HIV and cause the following except:
a) Cytopathic effects
b) Act as reservoir of HIV infection
c) Act as source of infection in nervous system
d) Defects in CD4+ T lymphocytes
5. In autoimmune haemolytic anaemia, the following type of immunologic tissue injury is involved:
a) Type I (anaphylactic)
b) Type II (cytotoxic)
c) Type III (immune complex)
d) Type IV (cell mediated)
6. Out of various antinuclear antibodies, pathognomonic of SLE is:
a) Antibody to single-stranded DNA
b) Antibody to double-stranded DNA
c) Antibody to histones
d) Antibody to nucleolar antigen
7. The most common form of amyloid in developing countries is:
a) Primary
b) Secondary
c) Hereditary
d) Localised
8. In cases of renal failure on long-term haemodialysis, there is development of following type of amyloid:
a) Amyloid light chain (AL)
b) Amyloid-associated protein (AA)
c) Amyloid β2 microglobulin (Aβ2m)
d) β amyloid protein (Aβ)
9. Cardiac amyloidosis often produces:
a) Dilated cardiomyopathy
b) Constrictive cardiomyopathy
c) Restrictive cardiomyopathy
d) Ischaemic cardiomyopathy
10. In senile cardiac amyloidosis, the biochemical form of amyloid is:
a) AL
b) AA
c) Aβ2M
d) ATTR