1. Apoptosis has the following features except:
a) There is cell shrinkage in apoptosis
b) There are no acute inflammatory cells surrounding apoptosis
c) There may be single cell loss or affect clusters of cells
d) Apoptosis is seen in pathologic processes only
2. Diabetic foot is an example of:
a) Dry gangrene
b) Gas gangrene
c) Wet gangrene
d) Necrotising inflammation
3. Idiopathic calcinosis cutis is an example of:
a) Necrotising inflammation
b) Dystrophic calcification
c) Metastatic calcification
d) Calcified thrombi in veins
4. In atrophy, the cells are:
a) Shrunken cells
b) Dead cells
c) Irreversibly injured cells
d) Reversibly injured cells
5. For metaplasia the following holds true:
a) It is a disordered growth
b) It affects only epithelial tissues
c) It is a reversible change
d) It is an irreversible and progressive change
6. Immune system in the body is activated by:
a) Cell adhesion molecules
b) Cytokines
c) G-protein receptors
d) Ion channels
7. In cell cycle, signal transduction system is activated by:
a) G protein receptors
b) Selectins
c) Cadherins
d) Integrins
8. Which of the following genes is proapoptotic:
a) p53
b) Bcl-2
c) RB
d) Bax
9. Annexin V is used as a marker for:
a) Necrosis
b) Fatty change
c) Apoptosis
d) Gangrene
10. Enzyme which prevents ageing is:
a) Catalase
b) Superoxide dismutase
c) Metalloproteinase
d) Telomerase