1. _________ link extracellular matrix to keratin intermediate filaments.
a) Integrins
b) Cadherins
c) Immunoglobulins
d) Selectins
Explanation: In hemidesmosomes, integrins attach to ECM proteins called laminins in the basal lamina, which is the ECM secreted by the epithelial cells. Integrins link ECM to keratin intermediate filaments. Hemidesmosomes are important in maintaining the structural stability of epithelial cells by anchoring them together indirectly through the extracellular matrix.
2. In focal adhesions, integrins attach ___________
a) integrins
b) cadherins
c) immunoglobulins
d) selectins
Explanation: In central bonds, integrins join fibronectins, a part in the extracellular network, to actin fibers inside cells. Connector proteins, for example, talins, vinculins, α-actinins and filamins, structure a complex at the intracellular space of integrins and tie to actin fibers. This multi-protein complex connecting integrins to actin fibers is significant for a get together of flagging edifices that go about as a sign for cell development and cell motility.
3. Dysfunction of cell adhesion occurs during cancer metastasis.
a) True
b) False
Explanation: Brokenness of cell bond happens during disease metastasis. Loss of cell-cell attachment in metastatic tumor cells enables them to get away from their site of root and spread through the circulatory framework.
4. ____________ polymers are considered to possess the property of biocompatibility.
a) Biodegradable
b) Bioequivalent
c) Bioavailable
d) Man-made
Explanation: Biodegradability is regularly a basic factor since frameworks ought to ideally be consumed by the encompassing tissues without the need for a careful evaluation.
5. What is the ideal composition of the polymer at the time of incorporation?
a) Liquid
b) Gas
c) Solid
d) Aerosol
Explanation: Preferably an injectable pre-polymer arrangement ought to be in fluid/glue structure, serializable without causing any major change, and have the ability to consolidate natural network necessities to be valuable in tissue building applications. Upon infusion, the pre-polymer blend should attach to the organic surface and fix to a strong and permeable structure with fitting mechanical properties to suit the application. The curing should be with minimal heat generation and the chemical reactions involved in curing should not damage the cells or adjacent tissues.
6. Biodegradable biomaterials are of two types, namely natural and __________
a) synthetic
b) protein-based
c) acrylic-based
d) ceramic
Explanation: Biodegradable biomaterials are of two types, namely natural and synthetic. The natural ones are based on proteins and polysaccharides. The synthetic ones are based on PGA, PLA, PAA, etc.
7. Biodegradable biomaterials have high process-ability into porous structures.
a) True
b) False
Explanation: Unlike ceramic biomaterials, Biodegradable biomaterials have high process-ability into porous structures and low brittleness.
8. What is the major drawback of biodegradable polymers?
a) Fast oxidation
b) Slow process-ability
c) Brittleness
d) Strength
Explanation: One of the obstacles in degradable metals improvement is quick oxidation bringing about early decay of mechanical properties and huge particle fixations in tissues.
9. Biodegradable biomaterials can only be degraded by enzymatic reactions.
a) True
b) False
Explanation: There are many possible mechanisms of degradation for materials in vivo, including stress cracking, fatigue cracking, hydrolysis, oxidation, and degradation by enzymes.
10. Biodegradable polymers can be used as a carrier for drugs.
a) True
b) False
Explanation: Polymers may likewise exemplify living cells or biomolecules which help in the mending procedure, anyway most debased manufactured polymer side-effects can’t be completely resorbed and are rather discharged by the body.