1. Which of the following is not the function of helper T cells is ____________
a) Produce soluble signaling proteins called cytokines, which include the interleukins
b) They help activate cytotoxic T cells to kill infected target cells
c) They help activate B cells to secrete antibodies and macrophages to destroy ingested microbes
d) They recognize and bind extracellular ligands
Explanation: The function of TH cells is to interact with macrophages and secrete cytokines that stimulate TC, TH and B cells to proliferate.
2. Which of the following is a function of Macrophages?
a) Ingest large particles and cells by phagocytes
b) Produce and secrete antibodies
c) Interact with infected host cells through receptors on T-cell surface
d) Interact with macrophages and secrete cytokines
Explanation: The remaining are the functions of B cells, TC and TH cells respectively.
3. Which of the following is a function of B lymphocytes?
a) Ingest large particles and cells by phagocytes
b) Produce and secrete antibodies
c) Interact with infected host cells through receptors on T-cell surface
d) Interact with macrophages and secrete cytokines
Explanation: The remaining are the functions of macrophages, TC and TH cells respectively.
4. Which of the following is a function of T lymphocytes?
a) Ingest large particles and cells by phagocytes
b) Produce and secrete antibodies
c) Interact with infected host cells through receptors on T-cell surface
d) Interact with macrophages and secrete cytokines
Explanation: The remaining are the functions of macrophages, B cells and TC respectively.
5. The most abundant immunoglobulin is ____________
a) IgA
b) IgE
c) IgG
d) IgM
Explanation: IgG is the most abundant antibody found in all body fluids.
6. Which of the following is the largest immunoglobulin?
a) IgA
b) IgE
c) IgG
d) IgM
Explanation: IgM is the largest pentameric type of antibody in the human circulatory system.
7. The antibody present in secretions like tears and saliva is ____________
a) IgA
b) IgE
c) IgG
d) IgM
Explanation: Secretory IgA is the main antibody present in mucous secretions and other secretions like tears and saliva.
8. Which of the following antibody first reaches the site of infection?
a) IgA
b) IgE
c) IgG
d) IgM
Explanation: IgM which is produced by B cells appears in response to the initial exposure to antigen.
9. Where do T-lymphocytes develop into fully competent but not activated T-cells?
a) The thymus gland
b) The lymph nodes
c) The thyroid gland
d) The bone marrow
Explanation: T cells are called so because they mature in the thymus gland.
10. Which of the following is true?
a) Most of the antibodies recognize small organic molecules
b) Most of the antibodies recognize proteins
c) Monoclonal antibodies produced in the laboratory lack the constant regions of IgG
d) IgM is a pentamer with 10 antigen binding sites
Explanation: Antibodies can recognize proteins like antigens.